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Gallbladder events : As with other incretin-based therapies, there is a potential risk of gallbladder disease, including cholelithiasis (gallstones)

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Lack of effect of islet amyloid polypeptide on hepatic glucose output in the in situ-perfused rat liver

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A 2026 ex-vivo study in human internal mammary artery tissue (Yildirim et al., J Clin Med 15(9):3488, PMID 42123221) provided the first human-tissue mechanism evidence for BPC-157s endothelium-dependent, nitric-oxide-mediated vasorelaxation anchoring the previously preclinical NO-pathway literature in human ex-vivo data